Dissolvable microneedle patch and method to produce dissolvable microneedle patch
AssigneeDarwin Precisions Corporation
InventorsJen Shun Lin, Jyun-Yi Yu, Yunpei Yang
Life of this patent
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Abstract
A dissolvable microneedle patch includes a microneedle portion and a patch portion. The microneedle portion has a base and a plurality of microneedles. The base has a first surface and a second surface opposite thereto. The microneedles are connected to the first surface. The patch portion is connected to the second surface. The microneedle portion is made from a mixture, and the mixture includes an excipient. The excipient includes sodium alginate and dextrin, and a weight ratio of the dextrin to the sodium alginate is 0.2 to 1. In addition, the present invention also provides a method to produce the dissolvable microneedle patch.
Claims8
A dissolvable microneedle patch, comprising:
- a microneedle portion, having a base and a plurality of microneedles, the base having a first surface and a second surface opposite thereto, and the microneedles being connected to the first surface;
- and
- a patch portion, connected to the second surface;
- wherein the microneedle portion is made from a mixture, the mixture comprises an excipient, the excipient comprises sodium alginate and dextrin, and a weight ratio of the dextrin to the sodium alginate is 0.2 to 1.
A method to produce a dissolvable microneedle patch, comprising:
- providing a mold formed with a plurality of grooves;
- injecting an aqueous solution into the mold;
- drying the aqueous solution to form a microneedle substrate, the microneedle substrate comprising a plurality of microneedle portions, each of the microneedle portions comprising a base and a plurality of microneedles, and the microneedles each having a shape corresponding to each of the grooves;
- gluing a plurality of patch materials to the microneedle portion;
- and
- cutting the microneedle substrate to form a plurality of the dissolvable microneedle patches;
- wherein a mixture of an excipient and a functional ingredient is dissolved in the aqueous solution, the excipient comprises sodium alginate and dextrin, and a weight ratio of the dextrin to the sodium alginate is 0.2 to 1.
Dependencies are inferred from the claim text.