Device for viable neotissue and stem cell transplant and methods of injection

An injection device for delivery of viable neotissue comprising:

• a fluid exchange chamber having a funneled portion, the funneled portion having a bottom connected to a pre-injection tube,
• wherein the fluid exchange chamber comprises fluid transfer holes extending through an outer surface of the fluid exchange chamber;
• a cylindrical outer shell comprising a central bore connecting a top inlet and a bottom outlet, wherein the fluid exchange chamber is disposed in the outer shell and wherein the pre-injection tube exits the shell via the bottom outlet;
• a first plunger having a central channel and a tapered bottom, wherein the tapered bottom mates with an inside of the funneled portion when depressed;
• and
• a stylet plunger disposed in the central channel, wherein the fluid transfer holes are angled upward from an inner surface of the fluid exchange chamber to the outer surface of the fluid exchange chamber.

An injection device for delivery of viable neotissue comprising:

• a fluid exchange chamber having a funneled portion, the funneled portion having a bottom connected to a pre-injection tube,
• wherein the fluid exchange chamber comprises fluid transfer holes extending through an outer surface of the fluid exchange chamber;
• a cylindrical outer shell comprising a central bore connecting a top inlet and a bottom outlet, wherein the fluid exchange chamber is disposed in the outer shell and wherein the pre-injection tube exits the shell via the bottom outlet;
• a first plunger having a central channel and a tapered bottom, wherein the tapered bottom mates with an inside of the funneled portion when depressed;
• and
• a stylet plunger disposed in the central channel, wherein the fluid transfer holes have a smaller diameter on an inner surface of the fluid exchange chamber than on the outer surface.

An injection device for delivery of viable neotissue comprising:

• a fluid exchange chamber having a funneled portion, the funneled portion having a bottom connected to a pre-injection tube,
• wherein the fluid exchange chamber comprises fluid transfer holes extending through an outer surface of the fluid exchange chamber;
• a cylindrical outer shell comprising a central bore connecting a top inlet and a bottom outlet, wherein the fluid exchange chamber is disposed in the outer shell and wherein the pre-injection tube exits the shell via the bottom outlet;
• a first plunger having a central channel and a tapered bottom, wherein the tapered bottom mates with an inside of the funneled portion when depressed;
• and
• a stylet plunger disposed in the central channel wherein a stylet base flange and a plunger flange are connected by a spring or a piston.

An injection device for delivery of viable neotissue comprising:

• a fluid exchange chamber having a funneled portion, the funneled portion having a bottom connected to a pre-injection tube, wherein the fluid exchange chamber comprises:
• fluid transfer holes extending through an outer surface of the fluid exchange chamber, wherein the fluid transfer holes are angled upward from an inner surface of the fluid exchange chamber to the outer surface of the fluid exchange chamber and wherein the fluid transfer holes have a smaller diameter on the inner surface of the fluid exchange chamber than on the outer surface, and
• a threaded base surrounding the pre-injection tube and a complementary threaded ring inside a bottom of a cylindrical outer shell such that the fluid exchange chamber is threadably coupled to an interior surface of the outer shell;
• the outer shell comprising a central bore connecting a top inlet and a bottom outlet, wherein the fluid exchange chamber is disposed in the outer shell and wherein the pre-injection tube exits the shell into the bottom outlet;
• a first plunger having a central channel and a tapered bottom, wherein the tapered bottom mates with an inside of the funneled portion when depressed;
• a male Luer lock needle fitting in the threaded base;
• and
• a stylet plunger disposed in the central channel, wherein the stylet plunger comprises a base having a flange and a stylet cavity, and wherein a stylet is disposed in the stylet cavity.