# US 12,758,678 B2 · Multi-component system

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- Number: US 12,758,678 B2
- Document ID: US12758678B2
- Status: Granted
- Kind: B2
- Application number: 18/246,315
- Filed: 2021-09-24
- Published: 2023-12-07
- Granted: 2026-10-13
- Earliest claimed: 2020-09-24
- Assignees: COSA Group GmbH
- Applicants: COSA Group GmbH
- Inventors: Janine-Melanie Potreck
- Web page: https://patentgrep.com/patent/US12758678B2

## CPC

- A61L 24/0073: {with a macromolecular matrix}
- A61L 24/0015: {Medicaments; Biocides}
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

A multi-component system contains at least one first substance and at least one second substance, where the first substance and the second substance are present in one or more substance portions.

## Claims

### Claim 1

A multi-component system, comprising:
a first substance N1, and
a second substance N2,
wherein the first substance N1 is contained in a first capsule K1 and the second substance N2 is contained in a second capsule K2, and
wherein the first capsule K1 and the second capsule K2 are covalently linked to one another by a linker L1 arranged on the first capsule K1 and a linker L2 arranged on the second capsule K2, and wherein the first substance N1 in the first capsule K1 comprises a pharmaceutically active ingredient.

### Claim 2 (depends on 1)

The multi-component system according to claim 1, wherein a linkage between the first capsule K1 and the second capsule K2 is achieved via a bridge, wherein the bridge is formed by a linkage of a linker L1 arranged on the first capsule K1 and a linker L2 arranged on the second capsule K2.

### Claim 3 (depends on 2)

The multi-component system according to claim 2, wherein the linker L1 and the linker L2 are each selected from the group consisting of star polymers, biopolymers, alkanes, alkenes, alkynes, aliphatic chains, proteins, silk, polysaccharides, cellulose, starch, chitin, nucleic acid, synthetic polymers, homopolymers, polyethylenes, polypropylenes, polyvinyl chloride, polylactam, natural rubber, polyisoprene, copolymers, random copolymers, gradient copolymer, alternating copolymer, block copolymer, graft copolymers, acrylonitrile butadiene styrene (ABS), styrene acrylonitrile (SAN), butyl rubber, polymer blends, polymer alloys, inorganic polymers, polysiloxanes, polyphosphazenes, polysilazanes, ceramics, basalt, isotactic polymers, syndiotactic polymers, atactic polymers, crosslinked polymers, elastomers, thermoplastic elastomers, thermosetting polymers, semi-crystalline linkers, thermoplastics, cis-trans polymers, conducting polymers, linear polymers, polymers with multivalence, star-shaped polyethylene glycols, self-assembled monolayers (SAM), carbon nanotubes, ring-shaped polymers, dendrimers, ladder polymers and similar substances, supramolecular polymers, and any other type of linkage of the first capsule K1 and the second capsule K2 with a functional group.

### Claim 4 (depends on 3)

The multi-component system according to claim 3, wherein the functional group is selected from the group consisting of alkanes, cycloalkanes, alkenes, alkynes, phenyl substituents, benzyl substituents, vinyl, allyl, carbenes, alkyl halides, phenol, epoxides, ethers, peroxides, ozonides, aldehydes, hydrates, imines, oximes, semicarbazones, hemiacetals, hemiketals, lactols, acetal/ketal, aminals, carboxylic acid, carboxylic acid esters, lactones, orthoesters, anhydrides, imides, carboxylic acid halides, carboxylic acid derivatives, amides, lactams, peroxyacids, nitriles, carbamates, guanidines, carbodiimides, amines, aniline, hydroxylamines, hydrazines, hydrazones, azo compounds, nitro compounds, thiols, mercaptans, sulfides, phosphines, P- Ylene, P-Ylides, biotin, streptavidin, metallocenes, and the like.

### Claim 5 (depends on 1)

The multi-component system according to claim 1, wherein the first substance N1 in the first capsule K1 comprises an adhesive or a component of a multi-component adhesive.

### Claim 6 (depends on 1)

The multi-component system according to claim 1, wherein the second substance N2 in the second capsule K2 comprises at least one component of a multi-component adhesive,
wherein the multi-component adhesive is selected from the group consisting of epoxy adhesives and polyurethane adhesives.

### Claim 7 (depends on 1)

The multi-component system according to claim 1, further comprising:
at least one further substance N3, which is arranged in a capsule K3.

### Claim 8 (depends on 7)

The multi-component system according to claim 7, wherein the at least one further substance N3 in the capsule K3 comprises an adhesive, a component of a multi-component adhesive, or a sealing material.

### Claim 9 (depends on 7)

The multi-component system according to claim 7, wherein a shell of the first capsule K1, the second capsule K2, and/or the capsule K3 comprises at least one material selected from the group consisting of (co)polymer, wax, resin, protein, polysaccharide, gum arabic, maltodextrin, inulin, metal, ceramic, acrylate (co)polymer, microgel, phase change material, lipids, maleic formaldehydes, carbohydrates, and combinations thereof.

### Claim 10 (depends on 1)

A material, to which the multi-component system according to claim 1 is applied.

### Claim 11 (depends on 1)

A method, comprising:
treating a wound with the multi-component system according to claim 1.

### Claim 12 (depends on 1)

The multi-component system according to claim 1, wherein the first capsule K1 and the second capsule K2 are nanocapsules and/or microcapsules.

### Claim 13 (depends on 1)

The multi-component system according to claim 1, wherein the second substance N2 in the second capsule K2 comprises an adhesive or a component of a multi-component adhesive system.
