Immunogenic peptide
AssigneeUCL Business PLC
InventorsMatthew Bryan Reeves, Ilona Anna Baraniak, Paul David Griffiths
Life of this patent
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Abstract
The invention provides a human herpesvirus immunogenic peptide comprising a novel antigenic domain (AD) of glycoprotein B, termed AD-6. The invention also provides a nucleic acid sequence encoding said immunogenic peptide and an inhibitor that binds to said 5 immunogenic peptide. Also provided are an immunogenic composition, a pharmaceutical composition and a vaccine comprising said immunogenic peptide, nucleic acid sequence or inhibitor, and methods of treating or preventing a human herpesvirus infection.
Claims11
An immunogenic composition comprising a human herpesvirus immunogenic peptide comprising SEQ ID NO:
- 7, SEQ ID NO:
- 9 or SEQ ID NO:
- 11, or a sequence having at least 90% identity thereto, wherein the human herpesvirus immunogenic peptide is about 50 or fewer amino acids in length;
- and wherein the composition does not comprise other antigenic domains of glycoprotein B (gB).
An immunogenic composition comprising a human herpesvirus immunogenic peptide, wherein the immunogenic peptide consists of SEQ ID NO:
- 13, SEQ ID NO:
- 14, SEQ ID NO:
- 15, SEQ ID NO:
- 16, SEQ ID NO:
- 17, SEQ ID NO:
- 18, SEQ ID NO:
- 19, SEQ ID NO:
- 20, SEQ ID NO:
- 21, SEQ ID NO:
- 22, SEQ ID NO:
- 23, SEQ ID NO:
- 24, SEQ ID NO:
- 25 or SEQ ID NO:
- 26.
Dependencies are inferred from the claim text.