Anti-inflammatory composition comprising epimendium koreanum nakai, polygala tenuifolia wild, and polyporus umbellatus fries extracts or mixture thereof as active ingredient
AssigneeKorea Research Institute of Chemical Technology
InventorsHyoung-Yun Han, Jung-Hwa Oh, Seokjoo Yoon, Se-Myo Park, Mi-Sun Choi, Soojin Kim
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Abstract
The present invention relates to an anti-inflammatory composition comprising Epimedium koreanum Nakai, Polygala tenuifolia Willd, and Polyporus umbellatus Fries extracts or a mixture thereof as an active ingredient. The extracts and mixture prepared according to the present invention exhibit a high inhibitory effect against nitric oxide and a suppressive effect against the expression of iNOS and COX2 and thus can be advantageously used as an anti-inflammatory composition.
Claims12
A method of treating inflammatory bowel disease, comprising administering to a subject in need thereof a pharmaceutical composition comprising active ingredients,
- wherein the active ingredients consist of a mixture of water extracts of Epimedium koreanum Nakai, Polygala tenuifolia Willd, and Polyporus umbellatus Fries,
- wherein the water extract of Epimedium koreanum Nakai, water extract of Polygala tenuifolia Willd, and water extract of Polyporus umbellatus Fries are present in the mixture at a weight ratio of 1:0.5~2:0.5~2.
A method of ameliorating inflammatory bowel disease, comprising administering to a subject in need thereof a health functional food composition comprising active ingredients,
- wherein the active ingredients consist of a mixture of water extracts of Epimedium koreanum Nakai, Polygala tenuifolia Willd, and Polyporus umbellatus Fries,
- wherein the water extract of Epimedium koreanum Nakai, water extract of Polygala tenuifolia Willd, and water extract of Polyporus umbellatus Fries are present in the mixture at a weight ratio of 1:0.5~2:0.5~2.
Dependencies are inferred from the claim text.