Loading patent…
AssigneeHouse Wellness Foods Corporation
InventorsTsubasa Nakajima, Kohei Kitamura, Hiroko Nakai, Yoshitaka Hirose
Estimating the term…
A problem to be solved by the present invention is to provide a composition (1) for inhibiting differentiation of osteoclast precursor cells into osteoclasts, improving bone metabolism, and/or inhibiting bone density reduction, the composition (1) including a culture supernatant or a processed product thereof, the culture supernatant being obtainable by culturing immune cells in the presence of lactic acid bacteria or a processed product thereof, or a composition (2) for inhibiting differentiation of osteoclast precursor cells into osteoclasts, improving bone metabolism, and/or inhibiting bone density reduction, the composition (2) including Lactobacillus plantarum strain L-137 (Lactobacillus plantarum L-137) or a processed product thereof. These compositions solve the problem.
A method for inhibiting differentiation of osteoclast precursor cells into osteoclasts, the method comprising administering a culture supernatant to a subject, the culture supernatant being obtainable by culturing immune cells in the presence of Lactobacillus plantarum strain L-137 (Lactobacillus plantarum L-137, accession number FERM BP-08607) or the culture of said strain, wherein the immune cells comprise cells capable of ingesting lactic acid bacteria.
A method for inhibiting differentiation of osteoclast precursor cells into osteoclast, the method comprising administering Lactobacillus plantarum strain L-137 (Lactobacillus plantarum L-137, accession number FERM BP-08607) or the culture of said strain to a subject.
A method of producing a composition for inhibiting differentiation of osteoclast precursor cells into osteoclasts, and/or inhibiting bone density reduction, the method comprising:
Dependencies are inferred from the claim text.