Back to results
US 12,758,578 B2Granted
Anti-inflammatory dendrimer formulation for the treatment of psoriasis
AssigneesCentre National de la Recherche Scientifique (CNRS), Universite Paul Sabatier Toulouse III, Inserm (Institut National De La Santé Et De La Rechercher MéDicale
InventorsMuriel Blanzat, Ranime Jebbawi, Rémy Poupot, Cédric-Olivier Turrin, Michel Simon, Emily Clement, Hélène Labie, Abdelouahd Oukhrib
Life of this patent
Estimating the term…
Abstract
The present invention relates to sugar-derived catanionic surfactant vesicles comprising anti-inflammatory dendrimers and to their use as a medicament, more particularly in the treatment of psoriasis.
Claims11
A vesicle comprising:
- a catanionic surfactant of formula (I) or a mixture of catanionic surfactants of general formula (I):
- wherein
- is a sugar,
- R1 is selected from H and a linear or branched, saturated or unsaturated hydrocarbon chain of 1 to 20 carbon atoms,
- R2 is a linear or branched, saturated or unsaturated hydrocarbon chain of 1 to 20 carbon atoms,
- R3 and R4 are independently of each other a linear or branched, saturated or unsaturated hydrocarbon chain, of 1 to 19 carbon atoms;
- and
- a dendrimer of formula (II):
- wherein
- is selected from the pentoses, hexoses and groups of the following formulas:
- Z is selected from —CH2— and —CH═N—,
- R is selected from H and C1-C12-alkyl
- A is selected from
- where X is selected from S and O, and
- n is an integer between 3 and 8.
12 more elements
Dependencies are inferred from the claim text.