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US 12,758,534 B2Granted
Treatment and prevention of basal cell carcinoma with topical composition comprising patidegib
AssigneeSol-Gel Technologies Ltd.
InventorsMoshe Arkin, Ofra Levy-Hacham, Ofer Toledano, Ervin Epstein, Jean Tang
Life of this patent
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Abstract
Disclosed herein is a method of treatment and/or prevention basal cell carcinoma lesions, comprising topically administering a pharmaceutical composition comprising patidegib or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the subject has a genetic mutation PTCH.
Claims11
A method of treatment and/or prevention of basal cell carcinoma (BCC) lesions in a patient suffering from Gorlin syndrome, the method comprising
- screening the patient for genetic mutation PTCH1;
- and
- topically administering a pharmaceutical composition comprising patidegib or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, to the patient if the screening confirms that the patient has the genetic mutation PTCH1, and
- wherein the patidegib is in an amount of about 2% w/w to about 4% w/w.
1 more element
Dependencies are inferred from the claim text.