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US 12,758,502 B2Granted
Compositions and methods of use
OwnerFredric Jay Coheninventor
Life of this patent
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Abstract
Provided is a pharmaceutical composition comprising: (a) granules comprising an active pharmaceutical ingredient, and one or more intragranular excipients; and an extragranular portion comprising at least one release modifier. Also provided are process for the preparation and methods for the use of the pharmaceutical composition.
Claims1
A method of administering dichlorphenamide to treat primary hyperkalemic periodic paralysis or primary hypokalemic periodic paralysis in a human subject in need thereof, wherein the subject is being administered famotidine for the treatment of a disease or disorder, the method comprising:
- discontinuing administration of the famotidine to the subject, and
- administering dichlorphenamide in tablet form to the subject at an initial dose of 50 mg, once or twice daily, thereby avoiding concomitant administration of famotidine and dichlorphenamide to the subject.
Dependencies are inferred from the claim text.