Hydrogel implants for lowering intraocular pressure
AssigneeOcular Therapeutix, Inc.
InventorsMichael Goldstein, Arthur Driscoll, Charles D. Blizzard, Ankita Desai
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Abstract
Provided herein are sustained release biodegradable ocular hydrogel implants which are useful for lowering ocular pressure and for treating related conditions.
Claims15
A sustained release biodegradable intracameral hydrogel implant comprising travoprost and a polymer network, wherein the polymer network comprises a plurality of multi-arm polyethylene glycol (PEG) units, and wherein the polymer network is formed by reacting a plurality of polyethylene glycol (PEG) units selected from PEG with a succinimidylazelate end group (SAZ), PEG with a succinimidylglutarate end group (SG) and PEG with a succinimidylsuccinate end group (SS), with one or more PEG amine groups or lysine-based amine groups.
Dependencies are inferred from the claim text.