Devices and methods for treating a vessel in a subject

A vein denuding device comprising:

• a handle including a control element, the control element is coupled to a proximal end of the handle;
• a catheter member coupled to a distal end of the handle;
• and
• a denuding member including a generally straight proximal arm portion coupled to the distal end of the handle, and a coil tip portion located at a distal end of the arm portion, wherein the catheter member surrounds the coil tip portion in an undeployed position of the denuding member, and the coil tip portion extends distally beyond the catheter member in a deployed position of the denuding member,
• the coil tip portion is formed of a shape memory material, and the coil tip portion further includes:
• two circumferential loops forming an open lumen devoid of any structure inside the two circumferential loops, and
• a flat wire having a first planar side, a second planar side, and an externally facing surface normal to the first and second side, the externally facing surface includes a roughened surface including a plurality of contiguous abrasion elements.

A vein denuding device comprising:

• a handle including a control element, the control element is coupled to a proximal end of the handle;
• a catheter member coupled to a distal end of the handle;
• and
• a denuding member including a generally straight proximal arm portion coupled to the distal end of the handle, and a coil tip portion located at a distal end of the arm portion, wherein the catheter member surrounds the coil tip portion in an undeployed position of the denuding member, and the coil tip portion extends distally beyond the catheter member in a deployed position of the denuding member,
• the coil tip portion is formed of a shape memory material and further includes at least two circumferential loops that form an open lumen devoid of any structure inside the circumferential loops,
• the coil tip portion comprises an oversized outer diameter relative to a vessel lumen, and
• the coil tip portion is configured to exhibit increased hoop stress and elongate along a longitudinal axis of the device in response to circumferential compression of the coil tip portion resulting from a decrease in vessel diameter.