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US 12,758,128 B2Granted
Biosensor apparatus
AssigneeTaiwan Semiconductor Manufacturing Company, Ltd.
InventorsYu-Jie Huang, Jui-Cheng Huang, Allen Timothy Chang
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Abstract
A biosensor apparatus comprises a biosensor device and a cover that is configured to attach to the biosensor device. The biosensor device includes a surface section that is disposed above the user's skin and an implantable section that is injected into the user's skin. The implantable section includes a bending detector and sensing circuitry. The sensing circuitry includes one or multiples of a biomarker sensor array, a control biomarker sensor array, a temperature sensor, and/or a biofouling detector.
Claims20
A biosensor apparatus, comprising:
- a semiconductor biosensor device, comprising:
- a surface section comprising processing circuitry and a first contact pad, the processing circuitry comprising:
- an analog-to-digital converter (ADC);
- a processing device operably connected to the ADC;
- and
- a wireless communication device operably connected to the processing device and to an antenna;
- and
- an implantable section for implanting in a user's skin, the implantable section comprising:
- a bending detector;
- and
- a sensing region comprising:
- a plurality of biomarker sensor arrays, each biomarker sensor array comprising a plurality of biomarker sensors operable to detect a biomarker;
- a control biomarker sensor array comprising a plurality of biomarker-insensitive sensors;
- a biofouling detector;
- and
- a temperature sensor,
- wherein the sensing region and the bending detector are operably connected to the processing circuitry and the plurality of biomarker sensor arrays are operably connected to a select circuit that is operable to select a signal from a biomarker sensor in a biomarker sensor array in the plurality of biomarker sensor arrays, and including a comparator circuit, wherein the selected signal is input into a first input of the comparator circuit and a signal from a biomarker-insensitive sensor in the control biomarker sensor array is input into a second input of the comparator circuit and an output signal output from the comparator circuit is used for pH calibration;
- and
- a cover operable to attach to the semiconductor biosensor device, the cover comprising:
- a second contact pad electrically connected to the first contact pad;
- and
- the antenna.
19 more elements
A biosensor apparatus, comprising:
- a semiconductor biosensor device, comprising:
- a surface section comprising processing circuitry and a first contact pad;
- and
- an implantable section for implanting in a user's skin, the implantable section comprising:
- a bending detector;
- and
- a sensing region comprising:
- a plurality of biomarker sensor arrays, each biomarker sensor array comprising a plurality of biomarker sensors operable to detect a biomarker;
- a control biomarker sensor array comprising a plurality of biomarker-insensitive sensors;
- a biofouling detector;
- and
- a temperature sensor,
- wherein the sensing region and the bending detector are operably connected to the processing circuitry and the plurality of biomarker sensor arrays are operably connected to a select circuit that is operable to select a signal from a biomarker sensor in a biomarker sensor array in the plurality of biomarker sensor arrays, and including a comparator circuit, wherein the selected signal is input into a first input of the comparator circuit and a signal from a biomarker-insensitive sensor in the control biomarker sensor array is input into a second input of the comparator circuit and an output signal output from the comparator circuit is used for pH calibration;
- and
- a cover operable to attach to the semiconductor biosensor device, the cover comprising:
- a second contact pad electrically connected to the first contact pad;
- and
- an antenna,
- wherein the processing circuitry comprises a processing device and the cover comprises:
- an analog-to-digital converter (ADC);
- and
- a wireless communication device operably connected to the ADC and to the antenna.
19 more elements
A biosensor apparatus, comprising:
- a semiconductor biosensor device, including:
- a surface section including processing circuitry and a first contact pad;
- and
- an implantable section for implanting in a user's skin, the implantable section including:
- a bending detector;
- and
- a sensing region including:
- a plurality of biomarker sensor arrays, each biomarker sensor array including a plurality of biomarker sensors operable to detect a biomarker;
- and
- a control biomarker sensor array including a plurality of biomarker-insensitive sensors,
- wherein the plurality of biomarker sensor arrays are coupled to a select circuit that is operable to select a signal from a biomarker sensor in a biomarker sensor array in the plurality of biomarker sensor arrays, such that the selected signal is input into a first input of a comparator circuit and a signal from a biomarker-insensitive sensor in the control biomarker sensor array is input into a second input of the comparator circuit and an output signal output from the comparator circuit is used for pH calibration.
8 more elements
Dependencies are inferred from the claim text.