Automatic analyzer and method for optically analyzing a biological sample

An automatic analyzer for optically analyzing a biological sample, the analyzer comprising

• a flow-cell with a first inlet port for introducing the sample into the flow-cell, or
• means for applying the sample onto a specimen holder, the analyzer further comprising,
• a Fourier Ptychography Microscope (FPM) for optically analyzing the sample in the flow-cell by obtaining at least for a part of the sample situated within a first volume of the flow-cell multiwavelength FPM data or for optically analyzing the sample on the specimen holder by obtaining at least for a part of the sample situated within a first area on the specimen holder multiwavelength FPM data, and
• a control module comprising computer means which are configured for identifying regions of interest (38) based at least on part of the FPM data of the sample obtained by employing an artificial intelligence algorithm and for reconstructing an amplitude or phase image of the sample only in the regions of interest based on the FPM data for the regions of interest to minimize the computational time required for the FPM reconstruction process, wherein the multiwavelength FPM data comprises data measured at least at two different wavelengths.