Gas-less eluent generator
AssigneeDionex Corporation
InventorsYongjing Chen, Yan Liu
Life of this patent
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Abstract
An eluent generation module includes an electrolytic gas generator and an electrolytic eluent generator. The electrolytic gas generator includes a generation chamber having an inlet and an outlet; an outlet electrode within the generation chamber; a first ion exchange connector; a bulk solvent chamber separated from the generation chamber by the ion exchange connector; and a bulk solvent chamber electrode within the bulk solvent chamber. The electrolytic eluent generator includes an electrolyte chamber containing an aqueous electrolyte solution; an electrolyte chamber electrode within the electrolyte chamber; a second ion exchange connector; an eluent generation chamber separated from the electrolyte chamber by the second ion exchange connector; and an eluent generation chamber electrode.
Claims24
An eluent generation module comprising:
- an electrolytic gas generator including:
- a generation chamber having an inlet and an outlet;
- an outlet electrode within the generation chamber;
- a first ion exchange connector;
- a bulk solvent chamber separated from the generation chamber by the ion exchange connector;
- and a bulk solvent chamber electrode within the bulk solvent chamber;
- and
- an electrolytic eluent generator fluidly downstream of the electrolytic gas generator including:
- an electrolyte chamber containing an aqueous electrolyte solution;
- an electrolyte chamber electrode within the electrolyte chamber;
- a second ion exchange connector;
- an eluent generation chamber separated from the electrolyte chamber by the second ion exchange connector;
- and
- an eluent generation chamber electrode,
- wherein liquid exiting the outlet of the electrolytic gas generator contains electrolysis gas generated in the generation chamber and is supplied to the electrolytic eluent generator, and wherein electrolysis gas delivered from the electrolytic gas generator combines with electrolysis gas generated at the eluent generation chamber electrode within the eluent generation module.
A method of generating a gas-free base eluent, comprising:
- supplying a liquid to an inlet of an electrolytic gas generator, the electrolytic gas generator including a generation chamber having the inlet and an outlet;
- an outlet anode within the generation chamber;
- a first cation exchange connector;
- a bulk solvent chamber separated from the generation chamber by the cation exchange connector;
- and a bulk solvent chamber cathode within the bulk solvent chamber;
- applying a current across the outlet anode and the bulk solvent chamber cathode to generate O2 at the outlet anode;
- directing a liquid stream exiting the outlet of the electrolytic gas generator to an electrolytic eluent generator fluidly downstream of the electrolytic gas generator, the liquid stream containing the generated O2, generator, the electrolytic eluent generator including an electrolyte chamber containing an aqueous electrolyte solution, an electrolyte chamber anode within the electrolyte chamber, a second cation exchange connector, an eluent generation chamber separated from the electrolyte chamber by the second cation exchange connector;
- and an eluent generation chamber cathode;
- applying a current across the electrolyte chamber anode and the eluent generation chamber cathode to migrate electrolyte ions from the electrolyte chamber across the second cation exchange connector to form the base eluent in the eluent generation chamber;
- and
- reacting the O2 with H2 formed at the eluent generation chamber cathode to produce the gas-free base eluent.
A method of generating a gas-free acid eluent, comprising:
- supplying a liquid to an inlet of an electrolytic gas generator, the electrolytic gas generator including a generation chamber having the inlet and an outlet;
- an outlet cathode within the generation chamber;
- a first anion exchange connector;
- a bulk solvent chamber separated from the generation chamber by the anion exchange connector;
- and a bulk solvent chamber anode within the bulk solvent chamber;
- applying a current across the outlet cathode and the bulk solvent chamber anode to generate H2 at the outlet cathode;
- directing a liquid stream exiting the outlet of the electrolytic gas generator to an electrolytic eluent generator fluidly downstream of the electrolytic gas generator, the liquid stream containing the generated H2, the electrolytic eluent generator including an electrolyte chamber containing an aqueous electrolyte solution, an electrolyte chamber cathode within the electrolyte chamber, a second anion exchange connector, an eluent generation chamber separated from the electrolyte chamber by the second anion exchange connector;
- and an eluent generation chamber anode;
- applying a current across the electrolyte chamber cathode and the eluent generation chamber anode the migrate electrolyte ions from the electrolyte chamber across the second anion exchange connector to form the acid eluent in the eluent generation chamber;
- and
- reacting the H2 with O2 formed at the eluent generation chamber anode to produce the gas-free acid eluent.
Dependencies are inferred from the claim text.