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US 12,753,248 B2Granted
Compositions of hydroxypropyl-beta-cyclodextrin and methods of purifying the same
AssigneeBeren Therapeutics P.B.C.
InventorsSteven Pfeiffer, Dustin McMinn, Gabor Benkovics
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Abstract
The present disclosure relates to compositions comprising mixtures of hydroxypropyl-β-cyclodextrin, wherein the compositions may be isomerically purified. The disclosure also relates to methods of isomerically purifying a mixture of hydroxypropyl-β-cyclodextrins.
Claims23
A composition comprising a mixture of isomerically-purified hydroxypropyl β-cyclodextrin molecules wherein 60% to 100% of the hydroxypropyl-β-cyclodextrin subunits are substituted at the 2-O-position and the composition has an average degree of substitution from 4.00 to 8.00.
Dependencies are inferred from the claim text.