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US 12,753,244 B2Granted
Monoclonal antibody used for diagnosis and early onset of prostate cancer
AssigneeTaipei Medical University
InventorShian-Ying Sung
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Abstract
The present invention provides a monoclonal antibody designed for the diagnosis and early detection of prostate cancer, particularly in relation to a monoclonal antibody developed to target the specificity of soluble ADAM9 variants (sADAM9v2) secreted in the vicinity of prostate cancer.
Claims12
An antibody or antigen-binding fragment thereof, which binds to a sADAM9v2 protein or a partial peptide thereof, wherein the antibody or antigen-binding fragment thereof comprises:
- a heavy chain comprising
- CDR1 comprising the amino acid sequence of SEQ ID NO:
- 1,
- CDR2 comprising the amino acid sequence of SEQ ID NO:
- 2, and
- CDR3 comprising the amino acid sequence of SEQ ID NO:
- 3;
- and
- a light chain comprising
- CDR1 comprising the amino acid sequence of SEQ ID NO:
- 4,
- CDR2 comprising the amino acid sequence of SEQ ID NO:
- 5, and
- CDR3 comprising the amino acid sequence of SEQ ID NO:
- 6.
12 more elements
Dependencies are inferred from the claim text.