US 12,753,186 B2 · Compound and composition for preventing or treating neuroinflammatory brain diseases comprising same as active ingredient

Abstract

The present invention relates to a novel compound and a composition for preventing or treating neuroinflammatory brain diseases, the composition comprising same as an active ingredient and, more specifically, to a pharmaceutical composition for preventing or treating neuroinflammatory brain diseases and a food composition for preventing or ameliorating neuroinflammatory brain diseases, the compositions comprising a compound represented by Chemical Formula 1 as an active ingredient. The novel compound of the present invention can be effectively used to provide a therapeutic agent for preventing or treating neuroinflammatory brain diseases, a food for ameliorating neuroinflammatory brain diseases, or a functional food for enhancing a cognitive function.

Claims7

Dependent claims

A compound of Chemical Formula 1 below, an optical isomer thereof or a pharmaceutically acceptable salt thereof:

In Chemical Formula 1 above,
R1 is —C(═O)Ra, —CH2Rb or —CH═NCH2C≡CH,
Ra is any one selected from the group consisting of —H, —OH, —OCH3, —OCH2CH3, and —OCH2CH2CH3,
Rb is —ORb1 or halogen,
Rb1 is any one selected from the group consisting of —H, straight-chain or branched-chain C1-C5alkyl, —C(═O)Rb11,
Rb11 is a straight-chain or branched-chain C1-C8alkyl group or a straight-chain or branched-chain C6-C12 alkenyl group containing at least one double or triple bond between carbons,
Rb12 is any one selected from the group consisting of —H, —CH3, —CH2CH3, —CH2CH2CH3, halogen, —OCH3 and —OCH2CH3, —NO2 and a phenyl group, and
R2 is —H or halogen.

5 more elements

Dependencies are inferred from the claim text.

Compound and composition for preventing or treating neuroinflammatory brain diseases comprising same as active ingredient

Life of this patent

Compound and composition for preventing or treating neuroinflammatory brain diseases comprising same as active ingredient

Life of this patent

Abstract

Claims7