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US 12,753,176 B2Granted
Compound, preparation method thereof, and use thereof in preparation of anti-cancer drug
AssigneeTianjin Jikun Medical Technology Co., Ltd.
InventorsCheng Yang, Guang Yang, Honggang Zhou, Liang Zhang, Jian Li, Dongchao Lun
Life of this patent
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Abstract
The present disclosure relates to a pyrazolo[3,4-d]pyrimidine compound, a preparation method thereof, and use thereof in the preparation of an anti-tumor drug. This class of compound has an inhibitory effect on FGFR1-3 and exhibits an anti-proliferation effect on NCI-H1581 and SNU-16 cancer cell lines.
Claims9
A compound of formula I or a pharmaceutically acceptable salt thereof:
- wherein in formula I, Ar is
- R is H, CF3, (CH3)2NCH2, or CH3;
- and
- Linker is
1 more element
Dependencies are inferred from the claim text.