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US 12,753,158 B2Granted
Hyperbranched polyglycerol polyglycidyl ether and its use as crosslinker for polysaccharides
AssigneeBiopolimeri S.R.L.
InventorVincenzo Maria De Benedictis
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Abstract
The present invention relates to a hyperbranched polyglycerol polyglycidyl ether having a molecular weight from 750 to 15.000 Da; and an epoxy equivalent weight from 183 to 7.000 g/eq. It also relates to a crosslinked polysaccharide obtainable by crosslinking the polysaccharide with the hyperbranched polyglycerol polyglycidyl ether. The present invention also relates to processes for their preparation and their uses in therapy, cosmetic, agriculture and food field.
Claims13
A crosslinked polysaccharide of formula (III) or formula (IV)
- wherein the crosslinked polysaccharide is in the form of a hydrogel composition,
- wherein
- each R1 is independently selected from the group consisting of R2, R3, R4 and R5, wherein at least two R1 are R4;
- R2 is
- R3 is
- R4 is
- R5 is
- PS is a polysaccharide selected from the group consisting of hyaluronic acid, starch or a derivative thereof, glycogen, cellulose or a derivative thereof, pectin, lignin, inulin, guar gum, xanthan gum, alginic acids (alginates), heparin, chondroitin sulphate, dermatan sulphate, glucuronan, glucomannan, galactomannan and carrageenan;
- b is an integer selected from the group consisting of 1 to 70;
- c is an integer selected from the group consisting of 1 to 70;
- d is an integer selected from the group consisting of 1 to 70;
- and
- wherein the crosslinked polysaccharide has a crosslinking percentage from 0.077 to 0.450%.
10 more elements
Dependencies are inferred from the claim text.