Increasing peak VO2 in patients with HF using cardiac contractility modulation stimulation
AssigneeImpulse Dynamics NV
InventorsDavid Prutchi, Simeon Ioannis Kedikoglou, Angela Connolly Stagg
Life of this patent
Estimating the term…
Abstract
A method of increasing peak VO2 including selecting a patient having impaired peak VO2 and estimated to have a potential for improving peak VO2, and applying cardiac contractility modulation stimulation to the patient's heart. A method of increasing peak VO2 including detecting ventricle contraction using one or more leads in a patient's ventricle, and applying Cardiac Contractility Modulation stimulation to the patient's ventricle, after a delay from a time of the detecting, thereby increasing the patient's peak VO2. Related apparatus and methods are also described.
Claims16
A method of increasing peak VO2 comprising:
- selecting a patient having impaired peak VO2 and the patient not known to have a medical condition which may prevent increasing peak VO2 and estimated, based on pulmonary assessment, to have a potential for improving peak VO2;
- wherein the selecting comprises selecting a patient estimated to have a pulmonary reserve suitable to achieve an increase in peak VO2 in response to cardiac contractility modulation stimulation;
- and
- applying cardiac contractility modulation stimulation to the patient's heart.
A method of increasing peak VO2 comprising:
- receiving by a Cardiac Contractility Modulation device said one or more treatment plans to increase peak VO2 in a patient having impaired peak VO2;
- wherein said one or more treatment plans takes into account one or more parameters of the patient comprising a level of pulmonary reserve;
- detecting ventricle contraction using one or more leads in the patient's ventricle;
- and
- applying Cardiac Contractility Modulation stimulation to the patient's ventricle, according to said one or more treatment plans, during a ventricle refractory period,
- thereby increasing the patient's peak VO2.
A method of planning Cardiac Contractility Modulation treatment for a patient to increase peak VO2, the method comprising:
- selecting a patient having impaired peak VO2 and estimated, based on pulmonary assessment, to have a potential for improving peak VO2;
- and
- planning Cardiac Contractility Modulation Treatment for the patient.
A Cardiac Contractility Modulation device comprising:
- a controller;
- at least one sensor input coupled to the controller;
- and
- a memory coupled to the controller,
- wherein the memory comprises instructions that, when executed by the controller, cause the controller to decide, based on the sensor input, to increase peak VO2 by providing cardiac contractility modulation stimulation to the patient's heart;
- wherein the patient has impaired peak VO2 and has pulmonary reserve suitable to achieve an increase in peak VO2 in response to cardiac contractility modulation stimulation.
Dependencies are inferred from the claim text.