System and method for non-invasive brain stimulation of cognitive enhancement
AssigneeWashington University
InventorsShiNung Ching, Todd Braver, Matthew Singh, Jacob Wheelock
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Abstract
A non-invasive closed-loop transcranial electrical stimulation (tES) system is described. The tES system includes a stimulator configured to generate transcranial electrical current to a head of a subject and a tES computing device. The tES computing device is programmed to receive neuroelectrical signals acquired from the head of the subject while being stimulated with the transcranial electrical current and exogenously modify brain activities of the subject by the transcranial electrical current based on endogenous neural control mechanisms of the subject via a control loop having the neuroelectrical signals as reference signals to the stimulator.
Claims20
A non-invasive closed-loop transcranial electrical stimulation (tES) system, comprising:
- a stimulator configured to generate transcranial electrical current to a head of a subject;
- and
- a tES computing device, comprising at least one processor in communication with at least one memory device, and the at least one processor programmed to:
- receive neuroelectrical signals acquired from the head of the subject while being stimulated with the transcranial electrical current;
- and
- exogenously modify mechanisms by which electrical activity is generated within a brain of the subject and in response to sensory stimuli presented to the subject via a control loop that uses the neuroelectrical signals to tune a previously estimated electrical Mesoscale Individualized NeuroDynamic (MINDy) model of latent excitatory and inhibitory neural populations for the subject and generates transcranial waveforms based at least in part on the tuned MINDy model.
Dependencies are inferred from the claim text.