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US 12,751,935 B2Granted
Method of treating and ameliorating depression
AssigneesYale University, The United States Government as represented by the Department of Veterans Affairs
InventorDeepak Cyril D'Souza
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Abstract
Described herein is a method for treating, ameliorating, and/or preventing depression in a subject in need thereof. The method includes administering parenterally to the subject an effective amount of dimethyltryptamine (DMT) or a derivative thereof. Also described is a kit for performing methods described herein.
Claims38
A method of treating or ameliorating depression in a subject in need thereof, the method comprising:
- administering parenterally to the subject an effective amount of a dimethyltryptamine (DMT) compound,
- wherein the DMT compound is selected from the group consisting of DMT, a DMT salt, a DMT solvate, an isotopically labelled derivative of DMT, or any mixture thereof, and
- wherein a dose of the DMT compound ranges from 0.038 mg/kg to 0.38 mg/kg in terms of DMT content.
A kit for treating or ameliorating depression in a subject in need thereof, the kit comprising:
- a dimethyltryptamine (DMT) compound selected from the group consisting of DMT, a DMT salt, a DMT solvate, an isotopically labelled derivative of DMT, or any mixture thereof;
- and
- a manual instructing that:
- the DMT compound is to be administered parenterally to the subject in an effective amount,
- a dose of the DMT compound to be ministered ranges from 0.038 mg/kg to 0.38 mg/kg in terms of DMT content.
2 more elements
Dependencies are inferred from the claim text.