Intravascular pressure and flow data diagnostic systems, devices, and methods

A method of intravascular pressure and flow monitoring comprising:

• measuring a plurality of intravascular blood flow values, a plurality of proximal blood pressure values, and a plurality of distal blood pressure values during each of a plurality of heart cycles using one or more sensors, wherein:
• the one or more sensors are part of an intravascular guide wire-based probe disposed on a distal end of a guidewire, the one or more sensors comprising:
• an active resistor that is sensitive to temperature and pressure, and
• a passive resistor that is sensitive to temperature but is not sensitive to pressure;
• the plurality of distal blood pressure values are measured by performing steps comprising:
• processing a first electrical signal associated with the active resistor and the passive resistor, and
• determining the distal blood pressure values based on the first electrical signal, and
• the plurality of intravascular blood flow values are measured by performing steps comprising:
• processing a second electrical signal associated with the passive resistor, and
• determining the intravascular blood flow values using a transfer function based on the second electrical signal;
• receiving, at a control system, the plurality of intravascular blood flow values, the plurality of proximal blood pressure values, and the plurality of distal blood pressure values;
• determining, with the control system, a plurality of flow thresholds, including a flow threshold for each of the plurality of heart cycles, using the plurality of intravascular blood flow values;
• determining, with the control system, a proximal blood pressure value and a distal blood pressure value at a time of each flow threshold;
• calculating, with the control system, a diagnostic parameter based on the proximal blood pressure value and the distal blood pressure value at the time of each flow threshold;
• and
• causing, with the control system, a display to display the diagnostic parameter for the plurality of heart cycles.