Compositions and methods for parasite control

A method of reducing or treating an infestation with one or more ectoparasites, wherein the one or more ectoparasites comprises a mosquito, a flea or a tick, the method comprising:

• exposing the one or more ectoparasites to a compound of formula (I), optionally as a salt or crystal:
• wherein
• X is (i) C—R7, if the attached to X is a double bond, or (ii) C(R7)2 or N—R7, if the attached to X is a single bond,
• Y is (i) C—R8, if one of the attached to Y is a double bond, or (ii) C(R8)2 or N—R8, if none of the attached to Y is a double bond,
• R1 and R2 are each independently H, halogen, alkyl, heteroalkyl, alkenyl, alkynyl, optionally substituted aryl, or optionally substituted heteroaryl,
• R3, R4, and R5 are each independently H, alkyl, alkenyl, alkynyl, optionally substituted aryl, or optionally substituted heteroaryl, or
• wherein R3 and R5, are optionally taken together to form group Z, which is —CH2—CH2—, —CH2—NR9, or —NR9—CH2—, each R9 being independently H, or alkyl,
• , in each case, independently indicates a single bond or a double bond,
• A is a bond or -L1-L2-L3-L4-, L1 being connected to the ring comprising X and Y, wherein
• L1 is a methylene group,
• L2 is —O—,
• L3 is a bond,
• L4 is a bond,
• R7 and R8 are each independently H, or alkyl, and
• wherein an optional substituent of the optionally substituted aryl, and optionally substituted heteroaryl is/are each independently halogen, alkyl, haloalkyl, and/or heteroalkyl,
• wherein compounds of the following formula are excluded:
• wherein
• R represents hydrogen or C1-C5 alkyl, and
• represents a single or double bond.