Adjusting insulin therapy setting based on variability of blood glucose values

A method of adjusting insulin therapy settings for a person with diabetes that treats the diabetes by administering first and second types of insulin via a portable drug delivery device, the method comprising:

• storing, in a non-transitory storage medium of the portable drug delivery device, a second-type insulin dosage suggestion for a person with diabetes regarding a second type of insulin having an active time that is shorter than an active time for a first type of insulin;
• receiving, via a communication link between a blood glucose sensor and the portable drug delivery device, blood glucose data for the person with diabetes, the blood glucose data including blood glucose values for a plurality of days;
• receiving, by a processor of the portable drug delivery device, second-type insulin dosage times for the person with diabetes regarding the plurality of days;
• determining, by the processor of the portable drug delivery device, a first variability of the blood glucose values for a selected first period of time during the plurality of days based on a selected metric, wherein the selected first period of time includes multiple time segments from the plurality of days that correspond to each other, each time segment beginning a predefined elapsed time after a second type of insulin dosage time during a respective day of the plurality of days;
• modifying the second-type insulin dosage suggestion in the non-transitory storage medium based on only the determined first variability;
• and
• administering to a person with diabetes, via the portable drug delivery device, the second type of insulin according to the modified second-type insulin dosage suggestion.

A portable diabetes management device comprising:

• a processor;
• and
• a non-transitory storage medium having stored therein:
• a first-type insulin dosage suggestion for a person with diabetes regarding a first type of insulin having an active time that is longer than an active time for a second type of insulin;
• blood glucose data for the person with diabetes, the blood glucose data including blood glucose values for a plurality of days;
• and
• instructions that when executed cause the processor to:
• determine a first variability of the blood glucose values for a first period of time during the plurality of days, wherein the first period of time includes multiple time segments from the plurality of days that correspond to each other, each time segment beginning a predefined elapsed time after a second type of insulin dosage time during a respective day of the plurality of days;
• assess a first-type insulin dosage suggestion stored in the non-transitory storage medium with respect to only the determined first variability;
• modify the first-type insulin dosage suggestion stored in the non-transitory storage medium based on the assessment of the first variability indicating the first-type insulin dosage suggestion led to an undesirable blood glucose level;
• and
• administer to the person with diabetes, via an insulin injection pen of the portable diabetes management device, the first-type insulin based on the modified first-type insulin dosage suggestion.