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US 12,749,183 B2Granted
Imaging systems and methods useful for signal extraction
AssigneeSingular Genomics Systems, Inc.
InventorFedor Trintchouk
Life of this patent
Estimating the term…
Abstract
Disclosed herein, inter alia, are methods and systems of image analysis useful for identifying and/or quantifying features in patterns.
Claims29
A method of quantifying features in a repeating pattern of an object, the method comprising:
- obtaining a plurality of images of the object using a detection apparatus, wherein the plurality of images includes a repeating pattern of features having different signal levels;
- providing the images or image-related data to a computer, wherein the computer has parameter data that describe the repeating pattern of features;
- partitioning the image or the image-related data into a plurality of registration subimages on the computer;
- detecting on the computer the repeating pattern of features for each registration subimage, the detecting based on a correlation between at least an image of the plurality of images and a corrugation image, wherein the corrugation image is determined from the parameter data;
- assigning an index address for each feature of the repeating pattern of features, the assigning based on the correlation;
- and
- quantifying a signal level of each feature.
4 more elements
A non-transitory computer-readable medium containing instructions to configure a processor to perform operations comprising:
- obtaining an image of an object using a detection apparatus, wherein the image includes a repeating pattern of features having different signal levels;
- providing the image or image-related data to a computer, wherein the computer has parameter data that describe the repeating pattern of features;
- partitioning the image or the image-related data into a plurality of registration subimages on the computer;
- detecting on the computer the repeating pattern of features for each registration subimage, the detecting based on a correlation between at least an image of the plurality of images and a corrugation image, wherein the corrugation image is determined from the parameter data;
- assigning an index address for each feature of the repeating pattern of features, the assigning based on the correlation;
- matching the index address for each feature on the computer;
- and
- quantifying a signal level of each feature.
5 more elements
A system comprising:
- a processor;
- and
- a memory, wherein the processor and the memory are configured to perform operations comprising:
- obtaining a camera image of an object using a detection apparatus, wherein the camera image includes a repeating pattern of features having different signal levels;
- providing the camera image or image-related data to a computer, wherein the computer has parameter data that describe the repeating pattern of features;
- partitioning the camera image or the image-related data into a plurality of registration subimages on the computer;
- detecting on the computer the repeating pattern of features for each registration subimage, the detecting based on a correlation between at least an image of the plurality of images and a corrugation image, wherein the corrugation image is determined from the parameter data;
- assigning an index address for each feature of the repeating pattern of features, the assigning based on the correlation;
- matching the index address for each feature on the computer;
- and
- quantifying a signal level of each feature.
8 more elements
Dependencies are inferred from the claim text.