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US 12,748,098 B2Granted
Semiconductor device for determining a biomolecule characteristic
AssigneeTaiwan Semiconductor Manufacturing Company, Ltd.
InventorsKun-Lung Chen, Tung-Tsun Chen, Cheng-Hsiang Hsieh, Yu-Jie Huang, Jui-Cheng Huang
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Abstract
A semiconductor device includes a circuit layer and a nanopore layer. The nanopore layer is formed on the circuit layer and is formed with a pore therethrough. The circuit layer includes a circuit unit configured to drive a biomolecule through the pore and to detect a current associated with a resistance of the nanopore layer, whereby a characteristic of the biomolecule can be determined using the currents detected by the circuit unit.
Claims20
A method comprising:
- driving, by a circuit, a biomolecule through a pore in a liquid gated transistor;
- and
- outputting, by the circuit, a parameter associated with the biomolecule.
A device comprising:
- first and second chambers;
- a liquid gated transistor separating the first and second chambers;
- a circuit;
- and
- first and second electrodes, each of which is coupled to a respective one of the liquid gated transistor and the circuit, wherein the circuit is configured to apply a voltage across the first and second electrodes.
2 more elements
A system comprising:
- first and second chambers;
- a liquid gated transistor separating the first and second chambers;
- a pair of electrodes coupled to the liquid gated transistor;
- and
- a circuit configured to apply a voltage across the electrodes.
2 more elements
Dependencies are inferred from the claim text.