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US 12,748,069 B2Granted
Encoding state change of nanopore to reduce data size
AssigneeRoche Sequencing Solutions, Inc.
InventorsSantiago Fernandez-Gomez, Hui Tian, Bill Maney, Seung Shin
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Abstract
A system includes a circuit configured to detect a voltage corresponding to an electrical measurement of a nanopore. The system also includes a component configured to compare the voltage to another voltage. Based at least in part on the comparison, a one bit indicator is determined. The one bit indicator indicates whether the voltage indicates a change in a state of the nanopore. In the event it is determined that the voltage indicates the change in the state of the nanopore, a multiple bit signal is provided for output.
Claims15
A system, comprising:
- a circuit configured to generate a measurement value corresponding to a state of a nanopore;
- and
- a component configured to:
- identify, based at least in part on a nanopore state change indicator, whether the measurement value indicates a change in the state of the nanopore,
- responsive to determining that the measurement value does not indicate a change in the state of the nanopore, removing the measurement value from output data to reduce a size of the output data;
- or
- responsive to determining that the measurement value indicates a change in the state of the nanopore, compressing the output data based at least in part on characteristics of the output data.
4 more elements
Dependencies are inferred from the claim text.