Nutritional composition comprising miR-3126
AssigneeSociete des Produits Nestle S.A.
InventorsFrederic Raymond, Mohamed Nabil Bosco, Lorane Texari, Solenn Pruvost, Gregory Lefebvre
Life of this patent
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Abstract
A nutritional composition comprising miR-3126. miR-3126 or said nutritional composition for use as a medicament. Use of miR-3126 to modulate gene expression of one or more gene selected from: Ninein, Unc-13 homolog D, Sulfatase 2, IL-32, OXER1, TMEM127, Butyrophilin, Integrin subunit alpha 2, Integrin beta 1, tubulin alpha 4A, tubulin beta 6, tubulin beta 2A and tubulin beta 2B. A method of producing said nutritional composition.
Claims11
A nutritional composition comprising miR-3126, wherein at least 50% of the miR-3126 consists of miR-3126-5p, and the remainder of the miR-3126 consists of miR-3126-3p, and wherein the nutritional composition is in a form selected from the group consisting of an infant formula, a breast milk fortifier, and an infant formula fortifier.
A method of protecting gastrointestinal health in a subject, promoting gut barrier development and function in a subject, promoting growth and development in a subject, or reducing the risk of a subject developing infectious, lymphoproliferative disorders, allergic diseases, or inflammatory diseases, comprising administering to the subject a nutritional composition comprising miR-3126, wherein at least 50% of the miR-3126 consists of miR-3126-5p, and the remainder of the miR-3126 consists of miR-3126-3p, and wherein the nutritional composition is in a form selected from the group consisting of an infant formula, a breast milk fortifier, and an infant formula fortifier.
Dependencies are inferred from the claim text.