Microfluidic device chamber pillars

A microfluidic device comprising:

• a chamber having a plurality of sidewalls, a floor, a ceiling, and an inlet;
• and
• a plurality of pillars extending from the floor to the ceiling of the chamber, each pillar having a leading corner and a trailing corner opposite the leading corner,
• wherein for each pillar, the leading corner is closer to the inlet than the trailing corner is, and the trailing corner has an angle different than an angle of the leading corner and less than a threshold angle that is based on a fluidic contact angle and wherein each pillar has an orientation relative to the inlet defined by the leading corner and the trailing corner, and the orientations of the pillars relative to the inlet are radially aligned with the inlet and promote fluid flow from the inlet throughout the chamber without trapping gas at the sidewalls of the chamber.