US 12,746,377 B2Granted

Dynamically controlled cerebrospinal fluid shunt

AssigneeOaya, Inc.

InventorsSamuel Robert Browd, Ryan J. Douglas, Aaron Olafur Laurence Philippsen, Mark Drlik

Life of this patent

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Abstract

Apparatus and associated methods relate to smart shunt systems. In an illustrative example, a cerebrospinal fluid (CSF) shunt system includes an interface module and conduit(s) configured to provide selective fluid communication between a brain ventricle(s) and at least one reservoir. The interface module may be operably coupled to one or more control module(s). The control module(s) may, for example, be operably coupled to one or more actuator(s) and/or sensor(s) (e.g., in the interface module(s), external to the interface module(s)). The control module(s) may, for example, selectively operate one or more of the actuator(s) as a function of input received from one or more of the sensors based on one or more predetermined control profile(s). Various embodiments may advantageously dynamically (e.g., automatically) control physiological attributes (e.g., CSF attributes).

Claims20

Dependent claims

A cerebrospinal fluid shunt comprising:

a proximal conduit configured to be implanted in fluid communication at a distal end with a brain ventricle of a patient;
a distal conduit configured to be implanted in fluid communication at a distal end with a reservoir;
a dynamically controlled valve module operably coupled to the proximal end of the proximal conduit and the proximal end of the distal conduit, the dynamically controlled valve module selectively operable to permit fluid communication between the distal conduit and the proximal conduit;
a pressure sensor configured to detect a transient pressure in the ventricle;
one or more sensors operatively coupled to the proximal conduit and configured to collect physiological signals from the patient;
one or more actuators operatively coupled to the proximal conduit and configured to perform actions based on control signals;
and,
a control module in operable communication with the dynamically controlled valve, the pressure sensor, the one or more sensors, and the one or more actuators, such that, in response to detecting a transient pressure event in the ventricle that meets at least one criterion determined as a function of a predetermined control profile, then the dynamically controlled valve is operated to provide a corresponding predetermined flow profile between the distal conduit and the proximal conduit, wherein the control module:
analyzes a pressure waveform generated by the pressure sensor to detect and characterize transient pressure events;
extracts diagnostic information from the transient pressure events;
adjusts operation of the dynamically controlled valve based on the diagnostic information;
collects multiple physiological signals from the one or more sensors;
operates the one or more actuators based on the physiological signals from the one or more sensors;
and,
stores the physiological signals from the one or more sensors.

12 more elements

A cerebrospinal fluid shunt comprising:

a proximal conduit configured to be implanted in fluid communication at a distal end with a brain ventricle of a patient;
a distal conduit configured to be implanted in fluid communication at a distal end with a reservoir;
a dynamically controlled valve module operably coupled to the proximal end of the proximal conduit and the proximal end of the distal conduit, the dynamically controlled valve module selectively operable to permit fluid communication between the distal conduit and the proximal conduit;
a pressure sensor configured to detect a transient pressure in the ventricle;
one or more sensors operatively coupled to the proximal conduit and configured to collect physiological signals from the patient;
one or more actuators operatively coupled to the proximal conduit and configured to perform actions based on control signals;
and,
a control module in operable communication with the dynamically controlled valve, the pressure sensor, the one or more sensors, and the one or more actuators, such that, in response to detecting a transient pressure event in the ventricle that meets at least one criterion determined as a function of a predetermined control profile, then the dynamically controlled valve is operated to provide a corresponding predetermined flow profile between the distal conduit and the proximal conduit, wherein the control module:
analyzes a pressure waveform generated by the pressure sensor to detect and characterize transient pressure events;
extracts diagnostic information from the transient pressure events;
adjusts operation of the dynamically controlled valve based on the diagnostic information;
collects multiple physiological signals from the one or more sensors;
operates the one or more actuators based on the physiological signals from the one or more sensors;
and,
stores the physiological signals from the one or more sensors;
and,
an input/output module in operable communication with the control module, wherein the input/output module is configured to exchange signals with an external interface device.

14 more elements

A cerebrospinal fluid shunt comprising:

a proximal conduit configured to be implanted in fluid communication at a distal end with a brain ventricle of a patient;
a distal conduit configured to be implanted in fluid communication at a distal end with a reservoir;
a dynamically controlled valve module operably coupled to the proximal end of the proximal conduit and the proximal end of the distal conduit, the dynamically controlled valve module selectively operable to permit fluid communication between the distal conduit and the proximal conduit;
a pressure sensor configured to detect a transient pressure in the ventricle;
one or more sensors operatively coupled to the proximal conduit and configured to collect physiological signals from the patient;
one or more actuators operatively coupled to the proximal conduit and configured to perform actions based on control signals;
and,
a control module in operable communication with the dynamically controlled valve, the pressure sensor, the one or more sensors, and the one or more actuators, such that, in response to detecting a transient pressure event in the ventricle that meets at least one criterion determined as a function of a predetermined control profile, then the dynamically controlled valve is operated to provide a corresponding predetermined flow profile between the distal conduit and the proximal conduit, wherein the control module:
analyzes a pressure waveform generated by the pressure sensor to detect and characterize transient pressure events;
extracts diagnostic information from the transient pressure events;
adjusts operation of the dynamically controlled valve based on the diagnostic information;
collects multiple physiological signals from the one or more sensors;
operates the one or more actuators based on the physiological signals from the one or more sensors;
and,
stores the physiological signals from the one or more sensors;
and
a filter module disposed in fluid communication with the proximal conduit and the distal conduit, such that the filter module is configured to filter cerebrospinal fluid as the cerebrospinal fluid flows therethrough.

14 more elements

Dependencies are inferred from the claim text.

Facts

Application: 18/313,249Filed 5 May 2023 · us provisional application
Priority: 5 May 2022
Published: US 2023/0355937 A19 Nov 2023
Granted: 29 Sep 2026
Term ends: Not estimatedThe source records don’t support an estimate.

Classification4 codes

A61M 27/006
Implant devices for drainage of body fluids from one part of the body to another: cerebrospinal drainage; Accessories therefor, e.g. valves
A61M 2202/0464
Liquids: cerebrospinal fluid
A61M 2205/3331
Controlling, regulating or measuring: pressure; Flow
A61M
Devices for delivering substances into the body

Family

Application63/364,253Us provisional application · filed 5 May 2022
Application63/365,407Us provisional application · filed 26 May 2022
Application63/477,158Us provisional application · filed 23 Dec 2022
Application63/477,162Us provisional application · filed 23 Dec 2022
Application63/488,412Us provisional application · filed 3 Mar 2023
US 2023/0355937 A1Pre-grant publication · published 9 Nov 2023
US 12,746,377 B2This patent

From the US filing history. Foreign family members aren’t listed.