Dengue vaccine unit dose and administration thereof
AssigneeTakeda Vaccines, Inc.
InventorDerek Wallace
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Abstract
The invention relates to a single unit dose of a dengue vaccine composition and methods and uses for preventing dengue disease and methods for stimulating an immune response to all four dengue virus serotypes in a subject or subject population. The unit dose of a dengue vaccine composition includes constructs of each dengue serotype, such as TDV-1, TDV-2, TDV-3 and TDV-4, at various concentrations in order to improve protection from dengue infection.
Claims21
A method for vaccinating against dengue disease and yellow fever in a subject or a population of subjects, the method comprising:
- administering one unit dose of a dengue virus composition and administering a live attenuated yellow fever vaccine on the same day;
- wherein the method provides efficacy against yellow fever and dengue within three months after administration of both the one unit dose of the dengue virus composition and the live attenuated yellow fever vaccine;
- wherein the dengue virus composition is TAK-003.
A vaccine combination comprising (i) a unit dose of a dengue virus composition and (ii) a yellow fever vaccine,
- wherein the dengue virus composition is TAK-003.
Dependencies are inferred from the claim text.