Back to results
US 12,746,278 B2Granted
Compositions and methods for wound healing
AssigneeThe Regenents of the University of California
InventorsBrian P. Eliceiri, Dong Jun Park
Life of this patent
Estimating the term…
Abstract
The disclosure relates to pro-reparative extracellular vesicle (EV) compositions comprising at least one fusion protein located inside the EV, the at least one fusion protein having pro-reparative biological activity. The disclosure also relates to methods of promoting wound healing in a subject suffering from at least one of obesity, diabetes, and end-stage renal failure, the method comprising administering a therapeutically effective amount of the pro-reparative EVs of any preceding claim to a wound of a subject.
Claims19
A pro-reparative extracellular vesicle (EV) composition comprising:
- at least one fusion protein located inside the EV, the at least one fusion protein having pro-reparative biological activity in at least one of promoting wound healing and tissue regeneration, wherein the at least one fusion protein comprises a serine protease inhibitor.
Dependencies are inferred from the claim text.