Topical composition for treatment of pain and symptoms associated with rhinosinusitis, method of making, and method of use

A method for treating pain and/or Rhinosinusitis symptoms in a subject, comprising:

• applying a therapeutically effective amount of a topical composition to skin or membrane(s) of the subject;
• wherein the topical composition comprises a homogeneous mixture of a hydrophilic carrier;
• a therapeutically active ingredient comprising potassium bitartrate and at least one of potassium chloride, calcium chloride, and magnesium chloride;
• at least one essential oil;
• and water;
• wherein the hydrophilic carrier is a sprayable carrier and the topical composition is a spray;
• and
• wherein the topical composition has been incubated for 24 hours to 3 weeks at 25° C. to 32° C. in a medium of KCl/water.

A method for treating pain in a subject, comprising:

• applying a therapeutically effective amount of a topical composition to skin of the subject;
• wherein the topical composition comprises a homogeneous mixture of about 1% to about 10% by volume of a hydrophilic carrier;
• a therapeutically active ingredient comprising about 0.2% to about 3% by volume of potassium bitartrate and about 0.1% to about 5% by volume of potassium chloride;
• about 1% to about 20% by volume of at least one essential oil;
• and about 20% to about 97% by volume of water and at least one of a parasept, a coolant, a perfume, or a surfactant;
• and
• wherein the topical composition has been incubated for 24 to 48 hours at 25° C. to 32° C. in a medium of KCl/water.