Pharmaceutical kits and uses thereof for treating colorectal cancer
AssigneeAnbogen Therapeutics, Inc
InventorsTsu-An Hsu, Sue-Ming Chang, Chien-Ting Lin, Meng-Chieh Lin
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Abstract
This disclosure in general describes a pharmaceutical kit for treating colorectal cancer; the pharmaceutical kit comprises (E)-N-hydroxy-3-(1-(phenylsulfonyl)-indolin-5-yl)-acrylamide, and an anti-PD-1 or anti-PD-L1 antibody. Furthermore, this disclosure describes a method for treating colorectal cancer in a subject, comprising administering to the subject the aforementioned pharmaceutical kit, wherein the (E)-N-hydroxy-3-(1-(phenylsulfonyl)-indolin-5-yl)-acrylamide is given to the subject in a dosage ranging from about 10 μg/kg to 1 g/kg; and the anti-PD-1 or anti-PD-L1 antibody is administered to the subject at a dosage ranging from about 1 μg/kg to 100 mg/kg.
Claims11
A pharmaceutical kit for treating colorectal cancer in a subject, comprising
- a first container containing (E)-N-hydroxy-3-(1-(phenylsulfonyl)-indolin-5-yl)-acrylamide;
- and
- a second container containing an anti-PD-1 or anti-PD-L1 antibody.
Dependencies are inferred from the claim text.