Pharmaceutical formulation comprising polymeric micro-/nanofibers incorporating echinochrome A
AssigneeNational and Kapodistrian University of Athens
InventorsVasileios Roussis, Efstathia Ioannou, Stefanos Kikionis, Georgia Valsami, Panagiotis Mavrogiorgis, Paraskevi Papakyriakopoulou
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Abstract
The invention relates to the development of a new pharmaceutical formulation for use as a medicament, in particular in anti-inflammatory diseases, and comprises of polymeric micro-/nanofibers incorporating echinochrome A. The composition provides increased stability and solubility, as well as controlled release for echinochrome A, while offering the potential for its targeted delivery.
Claims9
A pharmaceutical composition for use as a medicament, comprising two or more biocompatible polymers or one or more diblock copolymer and echinochrome A characterized in that echinochrome A is incorporated in micro-/nanofibers of the biocompatible polymers or the diblock copolymer and that the said biocompatible polymers or the blocks of the said copolymer have different hydrophilicity and pH sensitivity so that the pharmaceutical composition provides controlled release and/or targeted delivery of echinochrome A in different pH environments.
Dependencies are inferred from the claim text.