Dynamic four-dimensional contrast enhanced tomosynthesis

A digital tomosynthesis device for guided use of a surgical instrument, the device comprising:

• one or more processors;
• and
• memory storing instructions that, when executed by the one or more processors, cause the device to:
• acquire, while the surgical instrument is inserted into an object and at a plurality of time-points, a series of projection images of the object, each of the projection images being associated with a corresponding time-point of a plurality of time-points, and the series of projection images being acquired over the plurality of time-points and at a plurality of angles, wherein at each time-point, a plurality of projection images are acquired, and wherein the plurality of projection images corresponds to a subset of angles less than the plurality of angles;
• and
• construct four dimensional image data from the series of projection images, wherein the four dimensional image data comprises a representation of the object from each of the plurality of angles for each of the plurality of time-points, wherein constructing the four dimensional image data comprises combining projection images from a first acquisition cycle with projection images from a second acquisition cycle.

A digital tomosynthesis system for guided use of a surgical instrument, the system comprising:

• a surgical instrument;
• and
• a computing device configured to:
• acquire, while the surgical instrument is inserted into an object and at a plurality of time-points, a series of projection images of the object, each of the projection images being associated with a corresponding time-point of a plurality of time-points, and the series of projection images being acquired over the plurality of time-points and at a plurality of angles, wherein at each time-point, a plurality of projection images are acquired, and wherein the plurality of projection images corresponds to a subset of angles less than the plurality of angles;
• and
• construct four dimensional image data from the series of projection images, wherein the four dimensional image data comprises a representation of the object from each of the plurality of angles for each of the plurality of time-points, wherein constructing the four dimensional image data comprises combining projection images from a first acquisition cycle with projection images from a second acquisition cycle.