Medical proto microelectrode, method for its manufacture, and use thereof
AssigneeNeuronano AB
InventorsJens Schouenborg, Johan Agorelius
Life of this patent
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Abstract
A proto-microelectrode, a proto-microelectrode bundle and array, a method of manufacture of the proto-microelectrode, and a method of using the proto-microelectrode, the proto-microelectrode being capable of forming a microelectrode upon implantation into soft tissue, and includes an oblong electrode body; an optional first coat of electrically non-conducting material on the electrode body; a second coat of water insoluble flexible polymer material enclosing, at a distance, the electrode body and the first coat, the second coat including one or more through openings; a first layer of ice disposed between the electrode body and the second coat.
Claims23
Proto-microelectrode capable of forming, upon insertion into soft tissue, a microelectrode, the proto-microelectrode comprising:
- an oblong electrode body of electrically conducting material having a front end and a rear end, the electrode body comprising metal or metal alloy or an electrically conducting form of carbon or an electrically conducting polymer or a combination thereof;
- an optional first coat of electrically non-conducting material on the electrode body extending along it from its rear end towards its front end, the electrode body comprising one or more sections not covered by the first coat;
- a second coat of water-insoluble flexible polymer material disposed at a distance from and enclosing the electrode body and, if present, the first coat or a portion thereof, the second coat comprising one or more through openings or windows;
- a first layer of ice comprising pharmacologically active agent disposed between the electrode body and the second coat.
Method of manufacture of a proto-microelectrode for insertion into soft tissue, comprising:
- providing a first pre-stage microelectrode comprising:
- an oblong electrode body of electrically conducting material having a front end and a rear end;
- optionally comprising a first coat of electrically non-conducting material on the electrode body extending along it from its rear end towards its front end, the electrode body comprising one or more sections not covered by the first coat;
- a second coat of water insoluble flexible polymer material disposed at a distance from and enclosing the electrode body or a portion thereof, the second coat comprising one or more through openings;
- a layer of porous carbohydrate material disposed between the electrode body and the second coat;
- providing a second pre-stage microelectrode by substituting the layer of porous carbohydrate material by water optionally comprising pharmacologically active agent;
- cooling the thus transformed second pre-stage microelectrode to a temperature capable of transforming the layer of water optionally comprising pharmacologically active agent to a first layer of ice for a time sufficient for complete transformation.
Dependencies are inferred from the claim text.