Neurotransmitter concentration measuring apparatus for providing second derivative-based neurotransmitter concentration measurement result of fast-scan cyclic voltammetry data and method thereof

A neurotransmitter concentration measurement method comprising:

• collecting, by a data collector, Fast-Scan Cyclic Voltammetry (FSCV) data in which a capacitive charge current is reflected in a faradaic current that changes according to neurotransmitter injection;
• extracting, by a data processor, the individual voltammogram in which the faradaic current and the capacitive charge current are reflected together for each scan by the background subtraction in relation to the peak voltage generated based on neurotransmitter injection in the FSCV data;
• processing, by the data processor, the FSCV data to convert the FSCV data to a faradaic current-type Second-Derivative-based Background Removal (SDBR) data, in which the capacitive charge current is subtracted from the FSCV data based on a second derivative for a voltage of the individual voltammogram,
• wherein the processing of the FSCV data comprises quantifying a curvature of a neurotransmitter peak by multiplying the extracted individual voltammogram by a negative value after the second derivative for the voltage of the extracted individual voltammogram;
• and
• providing, by a measurement result provider, a concentration measurement result of a neurotransmitter that changes according to the neurotransmitter injection based on the SDBR data.