Therapeutic bacteriophages

Abstract

There is provided a bacteriophage of the Myoviridae family, comprising a genome of circularly permuted double-stranded DNA at a length of 200 kbp or more; characterised in that the phage has any one or more of the following features: a) does not have a holin gene; and/or b) binds to the Salmonella lipopolysaccharide; and/or c) has only one tail fibre protein; and d) has a sequence with at least 95% sequence identity to SEQ ID NO. 7 and/or a sequence with at least 80% sequence identity to SEQ ID NO. 8. Suitably, the bacteriophage may be used to treat salmonella, in particular in the treatment of salmonella in pigs and fowl.

Dependencies are inferred from the claim text.