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US 12,741,990 B2Granted
Peptide for disassembly of protein aggregates and methods thereof
AssigneeIndian Institute of Science
InventorsPurusharth I Rajyaguru, Mani Garg, Nayana V
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Abstract
The present disclosure provides a novel, potent and effective disassembly biomolecule, specifically a peptide, and a robust method or a platform technology for synthesizing and/or identifying disassembly biomolecules that are capable of inducing disassembly of protein aggregates associated with neurodegenerative diseases.
Claims4
A peptide comprising an amino acid sequence of (FGGFRGRGG)n or a sequence having at least 90% sequence identity thereto, wherein ‘n’ is an integer from 2 to 8, and
- wherein said peptide is capable of disassembling protein aggregates associated with neurodegenerative diseases.
Dependencies are inferred from the claim text.