MC3-type lipids
AssigneeNanoVation Therapeutics Inc.
InventorsMarco A. Ciufolini, Fariba Saadati, Anthony C. Y. Tam, Daniel Kurek, Dominik Witzigmann, Jayesh Kulkarni
Life of this patent
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Abstract
Provided is lipid and methods of making such lipid, the lipid having the structure of: each R is independently an alkyl of C12 to C16, each alkyl having 1 to 3 C═C double bonds, wherein at least one of the double bonds is of Z geometry; R′ is an optional alkyl; W is O, NH or NR″, wherein R″ is a C1 to C3 alkyl group, such as a methyl; X is either absent or present, and if present, X is O, NH, or the NR″; and Z is an alkylamino chain as defined by [—(CH2)m—NG1G2G3], wherein m is 1-5 and G1 and G2 are, independently, the C1 to C3 alkyl group, G3 is absent, a hydrogen or the C1 to C3 alkyl group.
Claims11
A lipid having a structure of nor-MC3:
Dependencies are inferred from the claim text.