Local neural network for three-dimensional dose calculations

A system comprising:

• a server comprising a processor and a non-transitory computer-readable medium containing instructions that when executed by the processor causes the processor to perform operations comprising:
• receive a first data set corresponding to parameters of a radiation therapy delivery system for delivering a radiation field to a treatment volume, wherein the treatment volume is a patient volume or a phantom;
• and
• execute a neural network model to generate a three-dimensional radiation dose matrix for the treatment volume, the three-dimensional radiation dose matrix indicating a quantity of radiation delivered to a plurality of volume elements of the treatment volume,
• wherein the neural network model has been trained to determine the quantity of radiation delivered to the plurality of volume elements of the treatment volume based on the parameters indicated by the first data set, wherein the neural network model receives local dose calculation parameters for each voxel grid element of a high resolution voxel grid of the treatment volume, and wherein application of the neural network model to the local dose calculation parameters is independent for each respective voxel grid element of the high resolution voxel grid.