Modular extracorporeal light-based therapy system for sepsis and carbon monoxide poisoning

Abstract

A modular extracorporeal phototherapy system is disclosed for the treatment of both sepsis and carbon monoxide (CO) poisoning in critical care settings. The invention integrates ultraviolet C (UV-C) irradiation (250-270 nm) for pathogen inactivation and immune modulation, with visible light exposure (420-450 nm and 540-580 nm) to facilitate photodissociation of CO from hemoglobin and cytochrome oxidase. The device comprises a treatment chamber incorporated into a extracorporeal blood circuit, equipped with tunable or dual-mode light emitters and feedback-controlled dosing. The system features integrated real-time biomarker monitoring of reactive oxygen species (ROS), cytokines, and carboxyhemoglobin (CO-Hb) levels to optimize light dosage and treatment timing. Through shared hardware and software infrastructure, this system allows condition-specific treatment protocols using wavelength-targeted light therapy, enhancing clinical versatility and patient outcomes. Through shared hardware and software infrastructure, this system allows condition-specific treatment protocols using wavelength-targeted light therapy, enhancing clinical versatility and patient outcome.

Dependencies are inferred from the claim text.