Methods and systems for treating neurological movement disorders
AssigneeThe Regents of the University of California
InventorsPhilip A. Starr, Nicole Swann, Coralie de Hemptinne, Jill Ostrem
Life of this patent
Estimating the term…
Abstract
The present disclosure provides methods for detecting hyperkinetic state by measuring brain activity of a patient suffering from a movement disorder. Also provided are methods for modulating therapy in patients suffering from a movement disorder. Aspects of the methods include measuring activity in brain of the patient and changing a treatment regimen if hyperkinetic state is detected. Also provided are devices, systems, and kits that may be used in practicing the subject methods.
Claims14
A method of treating a movement disorder in a human patient, the method comprising:
- recording first electrical activity as a function of time with one or more recording leads, wherein each of the one or more recording leads used to record the first electrical activity is placed at the motor cortex, wherein the patient is receiving a treatment for the movement disorder;
- performing a frequency domain transformation of the first electrical activity;
- analyzing a set of frequency values in the range of 60 Hz to 90 Hz from the transformed first electrical activity;
- and
- modifying the treatment of the patient only when the analyzed set of frequency values has oscillatory activity in the range of 60 Hz to 90 Hz in the motor cortex in order to thereby decrease oscillatory activity in the range of 60 Hz to 90 Hz in the motor cortex, wherein oscillatory activity in the range of 60 Hz to 90 Hz is indicative of hyperkinetic state in the patient,
- wherein the treatment comprises deep brain stimulation (DBS), and
- wherein modifying the treatment comprises adjusting a parameter of DBS.
Dependencies are inferred from the claim text.