Leak-proof fluid connection system

An anti-leak injection port for a fluid connection device, the injection port comprising:

• a housing comprising a reception lumen and a delivery lumen, wherein the delivery lumen is transverse to the reception lumen and intersects a distalmost end of the reception lumen;
• a guide bush disposed within the reception lumen and configured to receive a fluid delivery device, wherein the guide bush comprises an inner lumen and an aperture fluidly connected to the inner lumen;
• and a resilient member disposed within the delivery lumen and configured to restrict fluid flow through the delivery lumen in a default position and to fluidly connect the fluid delivery device and the delivery lumen in a flow position, wherein the resilient member is configured to be compressed into the flow position when the guide bush receives the fluid delivery device;
• wherein the housing comprises slots, and the guide bush comprises keys that are movably coupled to the slots.