Polysaccharide-based hydrogel scaffolds for wound care

A hydrogel comprising a gellan gum polymer network and collagen for use in the wound treatment in a subject in need thereof,

• wherein said hydrogel comprises a full interpenetrating polymer network comprising:
• a thermally crosslinked collagen, and
• a ionically crosslinked gellan gum,
• wherein the hydrogel comprises from 0.2% (w/v) to 1% (w/v) gellan gum and from 0.1% (w/y) to 0.2% (w/v) of collagen, and
• wherein the full interpenetrating polymer network is obtained by ionically crosslinking the gellan gum using a divalent cation as ionic cross-linking agent, in the presence of the thermally crosslinked collagen, using Mg2+ as the ionic cross-linking agent,
• wherein the interpenetrating polymer network comprises from 0.01% (w/v) to 0.03% (w/v) Mg2+, and
• wherein the hydrogel has a storage modulus (G′) of 2000 to 3000 Pa, as measured at 1 Hz at 25° C.