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US 12,741,020 B2Granted
Method for establishing epicutaneously sensitized food allergy animal model
AssigneeZhejiang Gongshang University
InventorsLinglin Fu, Qiaozhi Zhang, Jinru Zhou, Gang Yu, Chong Wang
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Abstract
A method for establishing an epicutaneously sensitized food allergy animal model and belongs to the technical field of medical evaluation and detection. The method includes an allergen sensitization stage and an allergen challenge stage, wherein an MC903 ethanol solution containing OVA is smeared on the skin of experimental animals in the allergen sensitization stage, and the OVA dissolved in a buffer solution is used for an oral challenge in the allergen challenge stage.
Claims4
A method for establishing an epicutaneously sensitized food allergy animal model, comprising:
- an allergen sensitization stage and an allergen challenge stage,
- wherein an MC903 ethanol solution containing allergens is smeared on the skin of experimental animals in the allergen sensitization stage, wherein the allergens include ovalbumin (OVA), a concentration of OVA in the MC903 ethanol solution is 5 mg/mL, and a concentration of MC903 in the MC903 ethanol solution is 0.1 mM;
- and
- the allergens dissolved in a buffer solution is used for intragastric administration in the allergen challenge stage.
1 more element
Dependencies are inferred from the claim text.