C-terminus modified human papilloma virus type 6 L1 protein and use thereof
AssigneeChinese Academy of Medical Sciences
InventorsXuemei Xu, Baicheng Xia, Ting Zhang
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Abstract
The present application relates to a C-terminus modified human papillomavirus type 6 L1 protein and use thereof. Specifically, the present application relates to a C-terminus modified human papillomavirus (HPV) type 6 L1 protein, an encoded nucleotide thereof, a vector comprising the nucleotide, a cell comprising the vector, a pentamer or virus-like particle composed of the HPV6 L1 protein, a vaccine containing the pentamer or virus-like particle and a vaccine adjuvant, and the use thereof in prevention of HPV infection and HPV infection-related diseases.
Claims12
A C-terminus modified HPV6 L1 protein, which is as shown in the sequence selected from the group consisting of:
- SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4, SEQ ID No. 5, SEQ ID No. 6, SEQ ID No. 7, SEQ ID No. 8 and SEQ ID No. 9.
Dependencies are inferred from the claim text.