Solid-gas reaction to generate nitroxyl (HNO) in the gas phase
AssigneesThe Johns Hopkins University, Universidad De Buenos Aires, Consejo Nacional De Investgaciones Cientficas Y Tecnicas Conicet
InventorsJohn Pasquale Toscano, Jessica Zarenkiewicz, Guillermo Alejandro Carrone, Agostina Maria Mazzeo, Ernesto Jose Marceca, Juan Pellegrino, Fabio Ariel Doctorovich, Sebastian Suarez, Paola E. Vargas
Life of this patent
Estimating the term…
Abstract
Disclosed is a method for generating nitroxyl (HNO) in the gas phase, the method comprising contacting a solid base-catalyzed HNO donor with a gaseous base; or a solid acid-catalyzed HNO donor with a gaseous acid; to form HNO in the gas phase and methods of treating a disease or condition responsive to HNO therapy with the HNO formed in the gas phase.
Claims7
A method for generating nitroxyl (HNO) in the gas phase, the method comprising:
- contacting a solid reducing agent with gaseous NO with heating to minimize dimerization of the HNO to N2O to form HNO in the gas phase.
Dependencies are inferred from the claim text.